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簡(jiǎn)介:鹽酸異丙腎上腺素,Isoprenaline hydrochloride是一種非選擇性的β-腎上腺素能受體激動(dòng)劑,具有有效的外周血管擴(kuò)張劑,支氣管擴(kuò)張劑和心臟刺激活性。

鹽酸異丙腎上腺素物理化學(xué)性質(zhì):

密度

1.324 g/cm3

沸點(diǎn)

417.5oC at 760 mmHg

熔點(diǎn)

165-175 °C (dec.)(lit.)

分子式

C11H18ClNO3

分子量

247.719

閃點(diǎn)

179.7oC

精確質(zhì)量

247.097519

PSA

72.72

LogP

2.3221

外觀性狀

白色結(jié)晶粉末

儲(chǔ)存條件

本品應(yīng)密封于陰涼避光處保存。

穩(wěn)定性

Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents.

水溶解性

Soluble

 

鹽酸異丙腎上腺素詳細(xì)介紹:

中文名稱(chēng):

鹽酸異丙腎上腺素

中文別名:

鹽酸異丙腎上腺素;異丙腎上腺素鹽酸鹽;4-[(2-異丙氨基-1-羥基)乙基]-1,2-苯二酚鹽酸鹽;鹽酸異丙腎上腺素原藥;異丙腎上腺素;異丙腎上腺素鹽酸鹽 USP標(biāo)準(zhǔn)品

英文名稱(chēng):

Isoproterenol hydrochloride

英文別名:

isoprenaline hydrochloride;Isoproterenol, HCl;2-benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-hydrochloride;3,4-dihydroxy-alpha-((isopropylamino)methyl)-benzylalcohohydrochloride;alpha-(isopropylaminomethyl)-3,4-dihydroxybenzylalcoholhydrochloride;euspiran;isadrine;isoprenalinechloride;isopropylnorepinephrine-hydrochloride;isoproterenolmonohydrochloride;Isoprenaline HCl;Isolated soy protein;Isoproterenol Hydrochloride;Isoproterenol (hydrochloride);[3H]-Isoproterenol hydrochloride;Isomenyl;isoprenaline;Isoprenaline (hydrochloride);Isovon;isuprel;Mistarel;proternol;Saventrine IV;Suscardia;(±)-Isoproterenol hydrochloride;1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride;N-Isopropyl-DL-noradrenaline hydrochloride;3,4-Dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol hydrochloride;4-(1-Hydroxy-2-((methylethyl)amino)ethyl)-1,2-benzenediol hydrochloride;Aludrine hydrochloride;Isoproterenol HCl;Aerolone;Aerotrol;Izadrin;Vapo-Iso;DL-Isoprenaline hydrochloride;DL-Isoproterenol hydrochloride;Isuprel hydrochloride;Asthpul;Norisodrine hydrochloride;Isopropylarterenol hydrochloride;dl-Isadrine hydrochloride;(+-)-Isoproterenol hydrochloride;Norisodrine Aerotrol;Isoprenaline chloride;Isoproterenol monohydrochloride;(+-)-Isoprenaline hydrochl

CAS號(hào):

51-30-9

分子式:

C11H18CLNO3

分子量:

247.72

詳細(xì)描述

博飛美科商城提供的[Sigma-Aldrich]Isoprenaline Hydrochloride為博飛美科出品的其它生化試劑,產(chǎn)品穩(wěn)定,定制速度快,極大地方便了廣大科研客戶的使用需求。產(chǎn)品包裝為25G,安全運(yùn)輸。

屬性:

mp:165-175 °C (dec.) (lit.)

SMILES string:Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

InChI:1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI key:IROWCYIEJAOFOW-UHFFFAOYSA-N

包裝:

5, 25, 100 g in poly bottle

生化/生理作用:

β-腎上腺素受體激活劑,增加胞質(zhì)cAMP。

查詢關(guān)鍵詞:51-30-9,鹽酸異丙腎上腺素,Isoprenaline Hydrochloride,Sigma-Aldrich,上?,F(xiàn)貨,以Sigma官網(wǎng)為準(zhǔn)。

 

鹽酸異丙腎上腺素參考文獻(xiàn):

[1]. Degerman E, et al. Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation. Proc Natl Acad Sci U S A. 1990 Jan;87(2):533-7

[2]. Vannucci SJ, et al. Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine. Biochem J. 1992 Nov 15;288 (Pt 1):325-30.

[3]. Delpy E, et al. Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3. Br J Pharmacol. 1996 Oct;119(3):471-8.

[4]. Muller FU, et al. Isoprenaline stimulates gene transcription of the inhibitory G protein alpha-subunit Gi alpha-2 in rat heart. Circ Res. 1993 Mar;72(3):696-700.

[5]. Lei M, et al. Modulation of delayed rectifier potassium current, iK, by isoprenaline in rabbit isolated pacemaker cells. Exp Physiol. 2000 Jan;85(1):27-35.

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